Enterovirus (EV)-D68 in Pediatric Patients with Respiratory Tract Infection: the Circulation of new B3 Clade in Italy
نویسندگان
چکیده
1473. Enterovirus (EV)-D68 in Pediatric Patients with Respiratory Tract Infection: the Circulation of new B3 Clade in Italy Antonio Piralla, PhD; Nicola Principi, MD; Luca Ruggiero, PhD; Alessia Girello, MD; Federica Giardina, PhD; Elisa De Sando, MD; Gian Luigi Marseglia, MD; Fausto Baldanti, MD and Susanna Esposito, MD; Molecular Virology Unit, Microbiology and Virology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Pediatric Highly Intensive Care Unit, Univ Milan, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, Pediatric Highly Intensive Care Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico and University of Milan, Milan, Italy, Pediatric Clinic, University of Pavia and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Dept Pediatr, Univ Pavia, IRCCS San Matteo, Pavia, Italy, Università degli Studi di Perugia, Perugia, Italy
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1473. Enterovirus (EV)-D68 in Pediatric Patients with Respiratory Tract Infection: the Circulation of new B3 Clade in Italy Antonio Piralla, PhD; Nicola Principi, MD; Luca Ruggiero, PhD; Alessia Girello, MD; Federica Giardina, PhD; Elisa De Sando, MD; Gian Luigi Marseglia, MD; Fausto Baldanti, MD and Susanna Esposito, MD; Molecular Virology Unit, Microbiology and Virology Department, Fondazione...
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Despite the recent emergence of enterovirus D68 (EV-D68), its clinical impact on adult population is less well defined. To better define the epidemiology of EV-D68, 6,800 nasopharyngeal aspirates (NPAs) from 2010-2014 were subject to EV-D68 detection by RT-PCR and sequencing of 5'UTR and partial VP1. EV-D68 was detected in 30 (0.44%) NPAs from 22 children and 8 adults/elderlies. Sixteen patient...
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A fatal case associated with enterovirus D68 (EV-D68) infection affecting a 10-year-old boy was reported in Hong Kong in 2014. To examine if a new strain has emerged in Hong Kong, we sequenced the partial genome of the EV-D68 strain identified from the fatal case and the complete VP1, and partial 5'UTR and 2C sequences of nine additional EV-D68 strains isolated from patients in Hong Kong. Seque...
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